Endocrine Abstracts

Background: The surgical technique and the extent of thyroidectomy are related to parathyroid injury and hypoparathyroidism.Methods and results: We retrospectively analyzed the files of 552 patients who underwent thyroidectomy in our surgery department between 2015-2017 with the aim to assess the incidence and impact of intraoperative features that may predispose to postoperative hypoparathyroidism (PoSH).Results: 171 (30.97%) pati...

Introduction: Hyperthyroidism and thyrotoxicosis can have multiple etiologies, varying from the most frequent described in clinical practice (Graves disease, toxic nodular goiter, thyroiditis) to very rare causes such as anaplastic thyroid cancer, thyroid lymphoma, amyloidosis or even secondary malignancy of the thyroid gland.Case report: A 53 year old man presented to our department for progressive goiter enlargement in the last two months which was acc...

Introduction: We report a case of a pituitary insufficiency apparently resistant to treatment.Case report: A 74 year old patient was admitted through the ER in our department for a recently discovered pituitary macroadenoma. His general condition was poor in spite of the initiation of corticotherapy. Evaluation: Smoker, with no significant medical history, the BP: 100/60 mmHg, no orthostatic hypotension, disoriented, confused, with moderately altered gen...

Objectives: Post-surgical hypoparathyroidism (PoSH) is a common long-term complication after thyroid surgery. The reported median incidence rates of temporary and permanent PoSH was 27% and 1% respectively.Methods and results: We retrospectively analyzed the files of 552 patients who underwent thyroidectomy in our surgery department between 2015 and 2017 with the aim to assess the prevalence of PoSH and to identify patient and disease related factors ass...

Background: The association between differentiated thyroid carcinoma (DTC) and autoimmune thyroiditis (AT) has been reported in numerous studies, yet the impact of the concurrent presence of AT and DTC remains controversial.Methods: We retrospectively analysed the files of 493 patients submitted to thyroidectomy in our surgery department between January 2012 and September 2015.Results: A total of 86 patients with DTC were enrolled,...

Background: The role of inflammation in the pathogenesis of cancer and the mechanisms through which platelets can influence the aggressive behaviour of different types of cancer have been highlighted by a few studies.Methods: We retrospectively analysed the files of 493 patients submitted to thyroidectomy in our surgery department between 2012 and 2015. We assessed the relationship between differentiated thyroid cancer (DTC) and mean platelet volume (MPV...

Objectives: In recent studies, neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are being investigated as prognostic and diagnostic markers for many malignancies, including thyroid cancer. The aim of our study was to investigate if a relationship exists between NLR and PLR and thyroid cancer.Materials and methods: We retrospectively analysed the files of 953 patients who underwent thyroidectomy in our surgery department between...

Objectives: In the last decades, thyroid cancer incidence has increased all over the world. This may be due to heightened medical surveillance and more addressability to surgery, as many cancers are diagnosed while under 1 cm. The aim of our study was to obtain data about the prevalence and histological subtypes of primary thyroid carcinoma in patients undergoing thyroidectomy.Materials and methods: We retrospectively analysed the files of 953 patients w...